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Alpha-1 Antitrypsin


Results and Values

What do the test results mean?

Normal levels of A1AT in serum range from 93 to 224 mg/dl (milligrams per deciliter) in blood. If special test called serum protein electrophoresis is performed on the drawn blood, levels will range from 0 to 3.1 gm/dl (grams per deciliter).

Increased levels of this protein can occur whenever there is inflammation of some kind in the body or the body is subjected to stress.

Lower levels of A1AT may indicate:

  • cirrhosis or other liver disease
  • chronic obstructive pulmonary disease such as emphysema
  • tumors or abnormal growths of the liver
  • obstructive jaundice. This is yellowing of the skin that occurs when there is a blockage in the liver.
  • portal hypertension. This is high pressure in the liver's circulatory system.
  • alpha-1-antitrypsin deficiency. This means that the body has a shortage of this enzyme.

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