Medications such as ioloquinol, paromomycin, and diloxanide are used to kill the parasites in the intestines. Other medications, such as metronidazole, may be used to kill the organisms that have invaded the tissue. Surgery may be needed for complications like perforation of the bowel.
Side effects depend on the medication used. Metronidazole often causes nausea, vomiting, and diarrhea. Surgery carries a risk of bleeding, infection, and allergic reaction to anesthesia.
Amebiasis is usually cured with medication, and the person can go back to normal activities.
Stool samples are examined 1, 3, and 6 months after treatment to be sure the person is free of the parasite. Any new or worsening symptoms should be reported to the healthcare provider.