There are no known effective measures to prevent chronic fatigue syndrome.
The long-term effects of CFS relate to the person's severe fatigue. Affected people may be unable to work or go to school. They may lack the energy to form or keep relationships with other people. This can result in depression and a feeling of hopelessness. Friends and healthcare providers may also have a negative attitude toward a person with CFS.
Chronic fatigue syndrome is not contagious and poses no risks to others.