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Congenital Factor VIII Deficiency - Hemophilia A
- Overview, Causes, & Risk Factors
- Symptoms & Signs
- Diagnosis & Tests
- Prevention & Expectations
- Treatment & Monitoring
- Attribution
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Overview, Causes, & Risk Factors
Hemophilia A is an inherited condition. It results from a lack of an important blood clotting protein.
What is going on in the body?
An individual with hemophilia A has poor blood clotting. The missing clotting protein, which is called factor VIII, causes the problem. Hemophilia A is one of the most common inherited bleeding disorders. It affects primarily men.
What are the causes and risks of the disease?
Inheriting an abnormal X chromosome usually causes hemophilia. This chromosome is usually passed down from the mother. Men have only one X chromosome, while women normally have two. This means that a woman usually has to inherit two abnormal X-chromosomes, while men only need one, to get the disease. Because of this, males more commonly get hemophilia.