Creatine Kinase-Isoenzymes - CPK Isoenzymes

What do the test results mean?

If a disease process is taking place, the total amount of CPK will be high, and the individual isoenzyme increases are used to determine what part of the body is responsible for the increase in total CPK. For example, when a heart attack occurs, the total CPK becomes high because of an increase in the CPK-MB and CPK-MM isoenzymes. The normal total CPK level is roughly 25 to 175 units per liter. Normal values for each of the isoenzymes are as follows:

Abnormally high levels of CPK-BB may sometimes be seen in the following:

Abnormally high levels of CPK-MB may indicate the following:

Abnormally high levels of CPK-MM may indicate the following: