Fifth disease in children generally follows a certain pattern. While rash is the most striking symptom of fifth disease, the child may have the following symptoms several days before the rash appears:
A child with fifth disease generally has a bright-red rash on the cheeks that gives a "slapped cheek" appearance. This may be followed by a pink, lacy rash on the arms, legs, and trunk. The rash generally causes no discomfort but may be mildly itchy.
An adult with fifth disease may have no symptoms at all or may have the typical rash. The person may also have joint pain and swelling.