Treatment of erythema multiforme may involve the following:
A person with severe erythema multiforme may be transferred to a burn unit for specialized care.
Medications used to treat erythema multiforme may cause upset stomach, rash, or allergic reaction. Debridement of dead tissue may cause bleeding or infection.
Most people recover without a problem and can return to normal activities. However, the person is at higher risk for erythema multiforme in the future. If the condition is caused by herpes, a person may want to consider taking medications to prevent further herpes outbreaks. If erythema multiforme is caused by a medication, the person should avoid the medication in the future.
In mild cases, the skin is monitored until the rash disappears. Usually the affected person can do this monitoring at home. In serious cases, a person may need to be admitted to the hospital for closer monitoring. Any new or worsening symptoms should be reported to the healthcare provider.