Esophagitis
Overview, Causes, & Risk Factors
Esophagitis is an inflammation of the lining of the esophagus. The esophagus is
the tube that carries food from the mouth to the stomach.
What is going on in the body?
The lining of the esophagus becomes inflamed because of an infection or
something that has irritated the lining. Esophagitis is called acute when it
occurs suddenly. It is called chronic when it lasts for a long time.
What are the causes and risks of the disease?
Causes of esophagitis include:
infections by organisms such as candida, cytomegalovirus (CMV), or herpes simplex
diseases and conditions that weaken the immune system, such as HIV, poorly controlled diabetes,
immunodeficiency disorders,
chemotherapy, chronic steroid use, or
malnutrition
chemicals that are swallowed
pills that become stuck in the esophagus
gastroesophageal reflux disease,
or GERD, a condition in which stomach acid splashes back up into the
esophagus
medications and supplements such as nonsteroidal anti-inflammatory drugs,
alendronate, doxycycline, iron,
and
potassium
Symptoms & Signs
What are the signs and symptoms of the disease?
Symptoms of esophagitis include:
difficulty swallowing
pain that can range from mild to severe
a feeling that something is stuck in the throat
nausea or vomiting
loss of appetite
reluctance to eat because of pain while swallowing
fast breathing
chest pain
blood in the stools
increased salivation or drooling
Diagnosis & Tests
How is the disease diagnosed?
After a complete history and physical, any of these tests may be done:
endoscopy, which uses a scope,
or
long tube, to see the esophagus and look for possible causes of symptoms.
Biopsies may also be done with the
endoscope.
upper GI series, in which the
person swallows liquid barium, and X-rays are taken to follow the course of the
barium through the esophagus and into the stomach.
blood tests, including a complete blood count
(CBC), to check for infection
esophageal motility tests, to evaluate the movement of food through the
esophagus
pH tests, to measure the acid content of the esophagus
Other tests may be done, depending on the symptoms.
Prevention & Expectations
What can be done to prevent the disease?
Maintaining a healthy weight, avoiding
smoking, and limiting
alcohol
intake may decrease the risk of esophagitis. Other ways to decrease the risk
include:
eating a nutritious diet based on the
food guide pyramid
getting adequate rest
practicing safer sex
getting proper treatment for
GERD
Esophagitis caused by toxic substances can be avoided by:
storing chemicals in properly labeled containers and keeping them out of the
reach of children
always taking pills with adequate amounts of liquid and at least 15 minutes
before lying down
Prevention of esophagitis is not always possible.
What are the long-term effects of the disease?
If the cause of the esophagitis is an infection, and the infection is treated,
the inflammation may improve.
If a toxic chemical, such as lye, bleach, or gasoline is ingested, the
esophagus can perforate, or rupture. This
esophageal perforation can be fatal.
Conditions such as GERD can
irritate and narrow the esophagus. Chronic GERD can result in Barrett's esophagus. In Barrett's
esophagus,
the lining of the esophagus is so badly damaged that a new lining is formed.
The changes in the cells lining the esophagus pose an increased risk for esophageal cancer.
What are the risks to others?
Esophagitis itself is not contagious and poses no risk to others. If the cause
is an infection, such as herpes
simplex, the infection may be contagious.
Treatment & Monitoring
What are the treatments for the disease?
Treatment of esophagitis is directed at the cause. Treatment may include:
antibiotics, antiviral, or antifungal medications for infections
medications to treat underlying conditions, such as GERD or
diabetes
maintaining a healthy lifestyle
surgery to repair the esophagus
What are the side effects of the treatments?
Medications used to treat infections may cause allergic reactions, stomach upset, and headache. Surgery carries a risk of bleeding, infection, and
allergic reactions to anesthesia.
What happens after treatment for the disease?
For mild, intermittent symptoms, treatment with antacids, diet changes, and
activity recommendations may control symptoms. Recovery from surgery may be a
few days to several weeks depending on the procedure used.
How is the disease monitored?
Any new or worsening symptoms should be reported to the healthcare provider.
Careful attention to symptoms that recur is important so that early treatment
can begin.
Attribution
Author:David J. Craner, MD
Date Written:
Editor:Ballenberg, Sally, BS
Edit Date:01/31/01
Reviewer:Eileen McLaughlin, RN, BSN
Date Reviewed:07/05/01
Sources
Harrison's Principles of Internal Medicine, 1998, Fauci et al.
The Merck Manual of Medical Information, 1997.