Guillain-Barre Syndrome

What are the treatments for the condition?

Initial treatment of GBS focuses on life support. A ventilator, or artificial breathing machine, may be needed. Fluids can be given through an intravenous line. Food can be given through a tube into the stomach.

A procedure called plasmapheresis can be effective if used early in the course of the illness. Plasmapheresis removes antibodies that may be present in the bloodstream. It also provides the person with fluids or plasma that is free of the antibodies that trigger GBS.

Immunoglobulin therapy is also used to treat GBS. High doses of immunoglobulins, or proteins from the immune system of normal donors, are given to the person with GBS. For some unknown reason, these globulins reduce the body's attack on its own nerves.

Corticosteroids, such as methylprednisolone, are sometimes given together with plasmapheresis or immune serum globulin. However, their effectiveness is questionable, and they may worsen the disease.

What are the side effects of the treatments?

Plasmapheresis is associated with a small risk of getting bloodborne infectious diseases. Corticosteroids and immune globulins may increase the person's risk for many types of infection.

What happens after treatment for the condition?

Physical therapy may be ordered to prevent contractures and other complications. Along with occupational therapy, it can be helpful in restoring the person's normal level of function. Pain medicines and physical therapy may be needed if the person has chronic pain.

How is the condition monitored?

After the acute phase of GBS, the individual will have regular visits with the healthcare provider. Any new or worsening symptoms should be reported to the provider.