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Herpes Simplex Infections


Treatment & Monitoring

What are the treatments for the infection?

In most cases, herpes simplex blisters on the face are self-limiting. They will usually crust over and go away in about 2 weeks. If they last longer, a doctor should be consulted. Treatment for oral herpes includes the following:

  • diluted, or 1 1/2%, hydrogen peroxide mouth rinse
  • lip balm to soothe sores on the lips
  • penciclovir cream
  • prescription antiviral medicines, such as acyclovir, valacyclovir, and famciclovir
  • salt-water rinse, with 1/2 teaspoon salt in 8 ounces of warm water
  • sunblock cream for lip protection
  • Acyclovir is used to treat HSV in newborn babies and people with genital herpes who have faulty immune systems. Acyclovir or its relative, valacyclovir, can also be used to treat HSV in otherwise healthy people. Other treatment is aimed at preventing secondary infection and relieving symptoms.

    What are the side effects of the treatments?

    Antiviral medicines may cause nausea, vomiting, diarrhea, and allergic reactions. Creams and ointments may cause an allergic reaction in some individuals.

    What happens after treatment for the infection?

    Some people will have frequent recurrences of HSV. They sometimes benefit from taking acyclovir as a preventive measure.

    How is the condition monitored?

    Any new or worsening symptoms should be reported to a healthcare provider.


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