An immunodeficiency disorder describes any condition that weakens the body's ability to fight off infection.
An immunodeficiency disorder can be present at birth, such as severe combined immunodeficiency. It may also be acquired, such as acquired immunodeficiency syndrome (AIDS). A person who has one of these disorders is prone to develop infections. These infections often become severe.
The disorder may be genetic or acquired. AIDS, for example, is caused by a virus that can be spread by transfusion of contaminated blood, sexually, or by using contaminated needles. The risk of acquiring AIDS following blood transfusion has decreased due to routine testing of all blood products.