There is no special preparation required before this test. Certain tests cannot be performed on the same day as a liver-spleen scan. The x-ray department staff may ask a person whether or not he or she has had any of these tests recently. For instance, any test that requires a contrast material called barium inside the intestines may interfere with the liver-spleen scan. Women who are or may be pregnant should tell the x-ray department staff before having this test. This is because the radiation from this test may harm an unborn child.