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Attention, chocolate lovers: You may not be able to help yourselves. Swiss and British scientists have linked the widespread love of chocolate to a chemical "signature" that may be programmed into our metabolic systems.
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Numbness

Overview, Causes, & Risk Factors

Numbness is a term used to describe a lack of ability to feel touch, temperature, or pain.

What is going on in the body?

Different people mean different things when they use the word numb. As related to a physical complaint, most people use the term to describe a lack of ability to feel touch or pain on the surface of their bodies. In most cases, numbness is related to nerve damage.

What are the causes and risks of the condition?

There are many conditions that can cause numbness, including:

diabetes mellitus, a condition in which the level of sugar in the blood is too high. This slowly damages nerves over time. Diabetic neuropathy, or nerve damage from diabetes, is one of the most common causes of numbness.

toxins and drugs, such as alcohol, arsenic, and certain chemotherapy medications used to treat cancer

injury or trauma to an area, including previous surgery

carpal tunnel syndrome, which can cause numbness in the hand from pressure on a nerve

vitamin deficiencies, such as B1\ \B2\ \B6\ \pantothenic acid\ \folic acid\ \niacin\ \biotin\ Cobalamin is the general name for vitamin B12. ',CAPTION,'Vitamin B12');" onmouseout="return nd();">vitamin B12, vitamin B6, and vitamin B2\ \niacin\ \vitamin B6\ \vitamin B12\ \folate\ \biotin\ \pantothenic acid\',CAPTION,'Vitamin B1');" onmouseout="return nd();">thiamine

brain damage, such as from a stroke or brain tumor

cancer, especially lung cancer and breast cancer in the later stages, and blood cancers, such as multiple myeloma or lymphoma

infections, such as HIV, Borrelia burgdorferi.\ It is passed to humans through tick bites. ',CAPTION,'Lyme Disease');" onmouseout="return nd();">Lyme disease, and herpes zoster

hormone imbalances, such as low thyroid hormone levels called hypothyroidism, or high levels of growth hormone, sometimes called acromegaly

severe liver disease, such as cirrhosis

severe kidney disease, such as chronic renal failure

autoimmune disorders, conditions in which a person's immune system attacks his or her own body, such as multiple sclerosis or Guillain-Barre syndrome

anxiety, including a condition known as conversion disorder

inherited conditions, such as a rare condition called hereditary sensory neuropathy

Other causes are also possible. Sometimes, no cause can be found.

Symptoms & Signs

What are the signs and symptoms of the condition?

When someone complains of numbness, the healthcare provider will need more information. For instance, he or she may ask:

what the person means by the term numbness. This term may be used to describe a total lack of ability to feel, decreased ability to feel, weakness, or even an altered sensation.

where the numbness is located

when the numbness started

whether the numbness is constant or only happens at certain times

what medications or drugs a person takes, if any

what other medical conditions a person has, if any

whether the numbness is associated with any other symptoms, such as weakness, burning sensation, weight loss, or nausea

whether the numbness has changed over time

whether there is any history of injury to the numb area

Other questions may also be asked. Any other symptoms should be reported.

Diagnosis & Tests

How is the condition diagnosed?

Diagnosis starts with a history and physical exam. This may be all that is needed to make a diagnosis. In other cases, further testing is needed.

Blood tests can help diagnose hormone imbalances, HIV, diabetes, and other conditions. If multiple sclerosis is suspected, a special x-ray test of the brain, called a cranial MRI, may be ordered. In some cases, a test called electromyography, or EMG, is ordered. This test looks at how well the nerves work in the affected area and can determine the cause in some cases. In this test, special electrodes are hooked up to the skin and tiny shocks are delivered to the nerve while the response to the shocks is measured.

Prevention & Expectations

What can be done to prevent the condition?

Prevention is related to the cause. For instance, avoiding alcohol can prevent cases due to alcohol abuse. Safer sex practices can prevent many cases due to HIV. Many cases cannot be prevented.

What are the long-term effects of the condition?

Long-term effects are related to the cause. For instance, anxiety-related numbness is always short-term and causes no long-term physical effects on the nerves. Cancer can result in death. Strokes may cause permanent paralysis and make a person unable to talk in some cases. Continued alcohol abuse can result in liver, brain, and other organ damage.

What are the risks to others?

Numbness itself is not contagious and poses no risks to others. Certain infections that can cause numbness, such as HIV, are contagious.

Treatment & Monitoring

What are the treatments for the condition?

Treatment is related to the cause. For those with a previous injury, there is often no effective treatment. Some people try surgery to return some feeling to the affected area. Physical therapy may help, too.

Those with diabetes need to control their blood sugar with diet, exercise, and medications to prevent further nerve damage. People with anxiety can be treated with medications to reduce anxiety. People with cancer may need surgery, chemotherapy, or radiation therapy. If a drug or toxin caused the numbness, it should be stopped.

What are the side effects of the treatments?

Side effects depend on the treatments used. All medications have possible side effects. For instance, medications to treat diabetes may cause low blood sugar, liver damage, or allergic reactions. Specific side effects depend on the medications used. Surgery carries a risk of bleeding and infection.

What happens after treatment for the condition?

The outcome for numbness depends on the cause. If the cause can be treated, the numbness may or may not go away. When a low thyroid hormone level is the cause, for example, the numbness often goes away after the person is treated. Numbness due to diabetes or alcohol abuse rarely goes away even after treatment. Those with cancer may die if treatment is not effective.

How is the condition monitored?

The person can monitor his or her numbness at home and report any changes or response from treatment to the healthcare provider. Further monitoring depends on the cause. Those with diabetes, for instance, need to have their blood sugar levels checked frequently.

Attribution

Author:Adam Brochert, MD
Date Written:
Editor:Smith, Elizabeth, BA
Edit Date:07/06/00
Reviewer:Eileen McLaughlin, RN, BSN
Date Reviewed:07/13/01

Sources

Cecil Textbook of Medicine, 1996, Bennett et al.

Harrison's Principles of Internal Medicine, 1998, Fauci et al.

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