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Obstructive Uropathy


Overview, Causes, & Risk Factors

Obstructive uropathy is a blockage of the normal flow of urine somewhere along the urinary tract.

What is going on in the body?

The urinary tract consists of the kidney, the bladder, the ureters, and the urethra. Obstruction can occur anywhere along this tract. Obstruction of urine flow increases the pressure to the kidney and can result in acute renal failure.

What are the causes and risks of the condition?

Obstructive uropathy may be caused by:

  • kidney stones
  • urethral strictures, or narrowing of the urethra
  • pressure from nearby tumors
  • scarring from previous radiation therapy
  • urinary tract infection
  • cancer
  • neuromuscular disorders, such as diabetic neuropathy
  • Obstructive uropathy is more common in a person with:

  • sickle cell anemia
  • diabetes mellitus
  • neuromuscular disease
  • pregnancy
  • cancer
  • benign prostatic hyperplasia (BPH)
  • history of kidney stones
  • history of radiation therapy
  • uterine prolapse
  • certain congenital disorders that affect the urinary tract

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