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Porphyria


Symptoms & Signs

What are the signs and symptoms of the disease?

Symptoms vary, depending on the type of porphyria. Symptoms that may occur with most of the porphyrias include:

  • severe abdominal pain
  • chest pain
  • sensitivity to bright sunlight
  • muscle cramping and weakness
  • numbness and tingling of the legs and arms
  • Hepatic porphyria may cause these additional symptoms:

  • fever
  • vomiting
  • constipation
  • rapid heart beat
  • liver disease
  • psychiatric disturbances, such as depression or mania
  • leg pain
  • skin discoloration, itching, and blistering
  • changes in urine color to a red-brown
  • changes in tooth color

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