The medication pyridostigmine can make some people feel less tired. Several medications are being studied that may improve strength or help motor neurons to grow.
The role of exercise is much debated. Some healthcare providers think exercise can worsen the condition and that rest will preserve energy. Others believe that exercise, in moderation, can help. The current recommendation is to test people with PPS to find their tolerance. Tolerance is the level at which people begin to get tired or uncomfortable. People are then taught to exercise within their tolerance limits. They are learn to pace themselves so they do not become fatigued. There is ongoing debate about which types of exercise may be helpful and which types may be harmful.
All medications can have side effects. Medications that combat fatigue may cause sleep disorders such as insomnia in some people.
The course of post polio syndrome is unpredictable. However, a healthy lifestyle and exercise within tolerance can increase the individual's quality of life.
Regular visits to the healthcare provider are needed to monitor muscle weakness and fatigue over time.