A pyogenic granuloma is usually a bright red or dark purple-red blood vessel nodule. This lesion is dome-shaped, protrudes from the skin, and is usually solitary. It can bleed easily, especially after re-injury. The nodules seem to be more common on the face, hands, arms, and shoulders. At first the lesions may be about the size of a pinhead. They may grow rapidly up to 1 cm in size.