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Serum Hepatitis - Hepatitis B


Symptoms & Signs

What are the signs and symptoms of the infection?

With acute hepatitis B, symptoms can vary. In fact, sometimes there are no symptoms. This is called subclinical hepatitis. Hepatitis B can also cause symptoms similar to other types of hepatitis, such as:

  • nausea
  • jaundice. This skin yellowing usually lasts a week or 2 and is accompanied by darkened urine.
  • malaise, or a vague feeling of illness
  • fatigue
  • pain in the upper right of the stomach
  • hypoglycemia, or low blood sugar
  • diarrhea
  • mild fever
  • a somewhat enlarged and tender liver
  • weight loss as a result of loss of appetite
  • These symptoms may last 1 to 3 months. Only half of the people with hepatitis B will develop jaundice, a yellowing of the skin and eyes. The liver can be mildly enlarged and tender. There are usually no other physical signs.

    Symptoms of chronic hepatitis B infection also vary. There may not be any symptoms, or possibly only fatigue. There can be occasional worsening of symptoms that may resemble acute hepatitis. Persons with chronic hepatitis may develop cirrhosis, a long-term condition in which the normal tissue of the liver is replaced by scar tissue. Cirrhosis can lead to the following:

  • spider angiomata, which are small, red dots on the skin containing tiny blood vessels
  • palmar erythema, which is redness on the palms of the hands
  • blood clotting problems
  • ascites, an abnormal collection of fluid in the abdomen
  • jaundice
  • intestinal bleeding
  • edema, or swelling of the skin
  • change in mental status or level of consciousness
  • liver cancer
  • Rarely, acute fulminant hepatitis, which involves severe liver cell destruction and loss of liver function, occurs. It can be fatal. Symptoms include:

  • an enlarged, painful liver
  • enlarged spleen
  • severe jaundice
  • susceptibility to bleeding
  • encephalopathy, a disorder in the functioning of the brain
  • aplastic anemia in rare cases. Aplastic anemia is a condition in which the bone marrow cannot make enough red and white blood cells.

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