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Sugar Intolerance in Pregnancy - Gestational Diabetes


Overview, Causes, & Risk Factors

Gestational diabetes is an intolerance to glucose that first occurs, or is first detected, during pregnancy. Glucose is the main form of sugar in the body. Gestational diabetes occurs in 4% of all pregnancies.

What is going on in the body?

Glucose is an important source of energy used by the body's cells. When a person eats, the pancreas normally makes extra insulin. The insulin causes the glucose in the blood to move inside the body's cells. In a woman with gestational diabetes, the hormones produced in pregnancy block the effects of insulin. Glucose then builds up in the blood and the cells are left without a main source of energy. The result is a high level of glucose in the blood, a condition known as hyperglycemia. High blood sugar levels can damage the growth of the fetus. This may cause complications for both the mother and baby.

What are the causes and risks of the disease?

The following conditions may increase a woman's chance of developing gestational diabetes:

  • age over 25 years
  • family history of diabetes mellitus, including type 1 diabetes mellitus or type 2 diabetes mellitus in a sibling or parent
  • personal history of gestational diabetes
  • marked obesity
  • previous delivery of an infant with a birth weight of more than 9 pounds
  • a previous stillbirth
  • previous delivery of a child with birth defects
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  • glucose in the urine sample taken in the healthcare provider's office
  • being a member of an ethnic group with a high incidence of gestational diabetes. This includes women of Latino, African American, Native American, Asian, or Pacific Islands descent.

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