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Urine Osmolality - Urine Osmolality Test


Results and Values

What do the test results mean?

Normally, urine has an osmolality of 50 to 1,400 mOsm/kg H20 (milliosmoles per kilogram of water).

Abnormally high osmolality may be a sign of:

  • Addison's disease, which is caused by a deficiency of hormones produced in the adenal glands
  • irregularities in the secretion of antidiuretic hormone, or ADH. ADH helps the kidneys put water back into the bloodstream.
  • congestive heart failure, or a weakened heart that fails to pump enough blood to body cells
  • Abnormally low osmolality may be a sign of:

  • aldosteronism, a condition in which a person has too much of the hormone aldosterone, which helps the body break down and use sodium, chloride, and potassium
  • diabetes insipidus, a disease which causes increased thirst and urination
  • excessive fluid intake, which occurs when a person drinks too much fluid
  • kidney damage or disease
  • pyelonephritis, a kidney inflammation usually caused by an infection

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