Fat travels through the body in packages called lipoproteins. Very-low-density lipoprotein (VLDL) carries a type of fat known as triglycerides. This test measures the amount of VLDL in the blood. VLDL is usually measured with other lipoproteins, such as HDL and LDL. This is known as a lipid profile test.
The level of VLDL can help assess a person's risk of atherosclerosis, or clogged arteries. The test can also monitor how well medications prescribed to lower lipids are working.
The test is performed on a sample of blood. A needle is inserted into a vein, usually in the person's arm. Blood is then collected into a vial. A bandage and pressure are applied to the skin to prevent bleeding. The blood is sent to the lab for testing.
The person needs to refrain from eating for 12 to 14 hours before the test. Drinking water is permitted. A low-fat diet should be followed in the 2 weeks before the test.
Normal VLDL levels are 25% to 50% of total cholesterol. Higher amounts are linked to a higher risk of heart disease.
Reasons for high VLDL levels can include:
Low levels of VLDL can result from:
Author:Stephanie Slon, BA
Date Written:
Editor:Duff, Ellen, BA
Edit Date:04/21/00
Reviewer:Adam Brochert, MD
Date Reviewed:09/04/01
Mosby's Manual of Diagnostic and Laboratory Tests, 1998, Kathleen D. Pagana and Timothy J. Pagana, Mosby, St. Louis.
Triglycerides: Bad Actors or Innocent Bystander?, May 1998, Harvard Heart Letter.