Ulcer, duodenal

Ulcer, duodenal: An ulcer (a hole in the lining) of the duodenum (the first portion of the small intestine). Ulcer formation is related to H. pyloridus bacteria in the stomach, anti-inflammatory medications, and smoking cigarettes. Ulcer pain may not correlate with the presence or severity of ulceration. Diagnosis is made with barium x-ray or endoscopy. Complications of ulcers include bleeding and perforation. Treatment involves antibiotics to eradicate H. pyloridus, eliminating risk factors, and preventing complications.