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Medical Dictionary Terms Beginning with G

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Gene product

Gene product: The RNA or protein that results from the expression of a gene. The amount of gene product is a measure of the degree of gene activity.
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Gene testing

Gene testing: Testing a sample of blood (or another fluid or tissue) for evidence of a gene. The evidence can be biochemical, chromosomal, or genetic. The aim is to learn whether a gene for a disease is present or absent.
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Gene therapy

Gene therapy: The treatment of disease by replacing, altering, or supplementing a gene that is absent or abnormal and is responsible for the disease. In studies of gene therapy for cancer, researchers are trying to bolster the body's natural capa
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Gene, evolutionarily conserved

Gene, evolutionarily conserved: A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential. There is not an extra copy of that gene with which evolution can tinker. And changes
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Gene, marker

Gene, marker: A detectable genetic trait or segment of DNA that can be identified and tracked. A marker gene can serve as a flag for another gene, sometimes called the target gene. A marker gene must be on the same chromosome as the target gene a
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Gene, zygotic lethal

Gene, zygotic lethal: A gene that is lethal (fatal) for the zygote, the cell formed by the union of a sperm (male sex cell) and an ovum (female sex cell). The zygote would normally develop into an embryo, as instructed by the genetic material within the
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General paresis

General paresis: A part of late (&tertiary&) syphilis a decade or more after the initial infection, due to chronic inflammation of the covering and substance of the brain (meningoencephalitis) which results in progressive dementia and general
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Genes, breast cancer susceptibility

Genes, breast cancer susceptibility: Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have
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Genetic

Genetic: Having to do with genes, structures found in every cell of the body. Each gene contains information that directs the activities of cells and controls the way an individual develops.
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Genetic code

Genetic code: The correspondence of the base triplets (trios composed of A.T.G., or C.) in DNA with the amino acids. The discovery of the genetic code clearly ranks as one of the premiere events of what has been called the Golden Age of Biology (and Me
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Genetic screening

Genetic screening: Testing a population to identify individuals at risk for a genetic disease or for transmitting it. Newborns may be screened for PKU (phenylketonuria), Jews for the gene for Tay-Sachs disease, Blacks for the sickle cell gene, etc.
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Genital

Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)
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Genital herpes

Genital herpes: A viral infection transmitted through intimate contact with the moist mucous linings of the genitals. This contact can involve the mouth, the vagina or the genital skin. The herpes simplex type 2 virus enters the mucous membranes throug
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Genital wart

Genital wart: A wart that is confined primarily to the moist skin of the genitals. These warts are due to viruses belonging to the family of human papillomaviruses (HPVs) which are transmitted through sexual contact. The virus can also be transm
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Genitourinary (GU)

Genitourinary (GU): Pertaining to the genital and urinary systems.
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Genome

Genome: All of the genetic information, the entire genetic complement, all of the DNA possessed by any organism. There is, for example, the human genome, the elephant genome, the mouse genome, the yeast genome, the genome of a bacteria, etc. Humans (an
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Genome Research Institute, National Human

Genome Research Institute, National Human (NHGRI): One of the newest of the National Institutes of Health (NIH), NHGRIÆs mission in formal terms is to ôsupport the NIH component of the Human Genome Project, a worldwide research effort designed t
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Genome, chromosomal

Genome, chromosomal: All of the genetic information in the chromosomes of an organism. For humans, that is all of the DNA contained in our normal complement of 46 rod-like chromosomes in virtually every cell in the body. (Mature red blood cells, for on
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Genome, human

Genome, human: All of the genetic information, the entire genetic complement, all of the DNA in a person. Humanity’s DNA is the treasury of human inheritance. It is this extraordinary repository of genetic information which the Human Genome Projec
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Genome, mitochondrial

Genome, mitochondrial: The genetic information contained in the circular chromosome of the mitochondrion, a structure located outside the nucleus in the cytoplasm of the cell. The mitochondrial genome and the chromosomal (nuclear) genome together const
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