WEDNESDAY, Sept. 29 (HealthDayNews) -- A genetic test can pinpoint which patients with deadly brain tumors called glioblastomas will live longer if they take the drug temozolomide, says a study presented Wednesday at the European Organization for Research and Treatment of Cancer symposium in Geneva.

This test is conducted during tumor biopsies and can provide results within two to three days. If the test becomes widely implemented, it could make temozolomide a targeted treatment.

A gene called 0-6-methylguanine-DNA methyltransferase (MGMT) is the key to predicting which patients will benefit from temozolomide, which acts directly against DNA to slow down the replication of cancer cells.

Glioblastomas account for about 12 percent to 15 percent of all brain cancers. About two to three people per 100,000 are diagnosed with glioblastomas each year in the United States and Europe.

More information

The National Cancer Institute has more about brain tumors.



-- Robert Preidt



SOURCE: European Organization for Research and Treatment of Cancer, news release, Sept. 29, 2004

Last Updated: Sep-29-2004