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Health Tip: Understanding Brittle Bone Disease

(HealthDay News) -- Osteogenesis imperfecta, also known as brittle bone disease, is an inherited condition in which the bones are more fragile and prone to fracture. It''s caused by an abnormality in collagen, a protein that helps bones form and keep their structure.

There are at least four recognized types of OI, and there may be more, the Brittle Bone Society says. Each type has differing clinical characteristics. DNA tests may help diagnose some cases, but these tests are not widely available and may take several weeks to complete.

There is no cure for OI, and treatments tend to focus on controlling symptoms. Common therapies include fracture care, surgery, physical therapy, and use of wheelchairs and other mobility aids.



-- Diana Kohnle

Last Updated: Jan. 05, 2007

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