Medicine Online
Any medical inquiries? Search MOL for answers:
NEWS
Home > News > 2007 > March > 30 > Curry Compound May Fight Rare Neurological Illness
Medical References
Diseases & Conditions
Women's Health
Mental Health
Men's Health
Medical Web Links
MOL Site Map
Medical Tips
Attention, chocolate lovers: You may not be able to help yourselves. Swiss and British scientists have linked the widespread love of chocolate to a chemical "signature" that may be programmed into our metabolic systems.
Read more health news

Curry Compound May Fight Rare Neurological Illness

FRIDAY, March 30 (HealthDay News) -- A synthetic compound that''s a distant chemical relative of a component of curcumin -- a spice used to make curry -- shows promise against an inherited neurodegenerative disorder called Kennedy''s disease, U.S. researchers say.

The disease, which affects only men, resembles a slowly progressive form of Lou Gehrig''s disease. There is no treatment for Kennedy''s disease, which is caused by a mutant gene.

The University of Rochester team found that ASC-J9, a synthetic chemical compound loosely based on a component of curcumin, dramatically slowed the progression of Kennedy''s disease in mice with the mutant human gene that causes the illness.

After treatment with ASC-J9, the mice showed improved muscle strength, could walk much more normally and had near-normal levels of a molecule that keeps nerve cells healthy.

The findings were published in the March issue of the journal Nature Medicine.

While ASC-J9 shows promise, much more research needs to be done to determine if ASC-J9 can be developed into a drug to help people with Kennedy''s disease.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about Kennedy''s disease.



-- Robert Preidt



SOURCE: University of Rochester Medical Center, news release, March 20, 2007

Last Updated: March 30, 2007

Copyright © 2007 ScoutNews, LLC. All rights reserved.