Medicine Online
Any medical inquiries? Search MOL for answers:
NEWS
Home > News > 2004 > December > 27 > Drug-Eluting Stents Work for Restenosis
Medical References
Diseases & Conditions
Women's Health
Mental Health
Men's Health
Healthy Choice News
Site Map Links
Medical Tips
Attention, chocolate lovers: You may not be able to help yourselves. Swiss and British scientists have linked the widespread love of chocolate to a chemical "signature" that may be programmed into our metabolic systems.
Read more health news

Drug-Eluting Stents Work for Restenosis

MONDAY, Dec. 27 (HealthDayNews) -- Drug-eluting stents greatly reduce the risk that arteries will renarrow in patients with in-stent restinosis -- artery narrowing caused by scar tissue -- according to a German study in the January issue of Catheterization and Cardiovascular Interventions.

The study noted that plaque-clogged arteries that are opened with a regular metal stent have a 1-in-3 chance of becoming narrowed again with scar tissue (restinosis). If this problem is treated using a metal stent or balloon angioplasty, the artery will narrow again in half the patients.

This study of 77 patients found a 13 percent rate of repeat in-stent restinosis among patients treated with a drug-eluting stent that slowly releases the drug sirolimus, which prevents formation of scar tissue. The in-stent restinosis repeat rate was 61 percent for patients treated with balloon angioplasty.

At the nine-month follow up, 14 percent of the patients treated with the sirolimus-eluting stent required yet another procedure to open the artery, compared with 32 percent of balloon angioplasty patients.

"Restinosis was dramatically lowered by drug-eluting stents as opposed to balloon angioplasty alone, and that resulted in a dramatic lowering in the major adverse cardiac event rate," researcher Dr. Rainer Hoffman from the University of Aachen said in a prepared statement.

More information

The U.S. Food and Drug Administration has more about stents.



-- Robert Preidt



SOURCE: Catheterization and Cardiovascular Interventions, news release, Dec. 27, 2004

Last Updated: Dec-27-2004
HomeSitemap Contact UsAdvertisingPress RoomGive Us Your FeedbackRead Our Terms & Conditions and Our DisclaimerPrivacy Statement