Health Tip: Rare Condition Predisposes People to Cancer

(HealthDay News) -- Some people are at high risk for colorectal cancer because of a genetic mutation known as Lynch syndrome.

People with Lynch syndrome have more than an 80 percent chance of developing colorectal cancer, usually at a younger age than colorectal cancer attributed to other causes, according to the Mayo Clinic.

Lynch syndrome is responsible for about 3 percent to 4 percent of colorectal cancer cases, the Mayo Clinic says.

Symptoms of Lynch syndrome, typical of colorectal cancer in general, include:

• Constipation or diarrhea that persists for several days.
• Visible blood in the stool.
• Abdominal cramps or pain.
• Fatigue or weakness.
• Loss of appetite.
• Unexplained weight loss.

Genetic testing can determine if you have the disorder.

-- Deborah DiSesa Hirsch

Last Updated: Feb. 23, 2006