NEW YORK, Oct 6, 2005 (UPI via COMTEX) -- Scientists in New York City say long-term use of non-steroidal, anti-inflammatory drugs cuts in half the risk of oral cancer in smokers.
However, the same researchers -- after an analysis of 20 years of data on the health of more than 900 people -- found long-term use of NSAIDs, such as ibuprofen and naproxen, doubled the risks for cardiovascular death.
The collaborative research looked at the use of NSAID pain relievers for six months or more.
The study was conducted by researchers at the Norwegian Radium Hospital and The National Hospital in Oslo; University of Science and Technology, Trondheim, Norway; New York-Presbyterian Hospital/Weill Cornell Medical Center in New York City; The University of Texas M.D. Anderson Cancer Center in Houston; and the University of Helsinki.
"Our findings highlight how a commonly used drug can have a benefit from the standpoint of cancer prevention, but can also have side effects -- in this case, an increased risk for cardiovascular death," said co-researcher Dr. Andrew Dannenberg of Cornell University.
The research appears online in The Lancet.
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