CF - Cystic Fibrosis

How is the disease diagnosed?

Family history, persistent respiratory disease, or clinical evidence of pancreatic insufficiency may suggest the diagnosis of cystic fibrosis. The diagnosis requires an abnormal sweat chloride test. In this test, a chemical is used to stimulate sweat production. The amount of chloride in the sweat is then measured.

Screening for pancreatic insufficiency is done by measuring the levels of two enzymes in the stool. This test is not as reliable as measuring the sweat chloride level.

Lung function testing can identify certain abnormalities in the way the lungs and airways work. These abnormalities may be caused by problems other than cystic fibrosis.