A Pap smear is not intended to diagnose uterine cancer. This test is used to diagnose cancer of the cervix. However, Pap smears occasionally show changes in endometrial cells. If this occurs, a biopsy or dilatation and curettage, or D&C, will be done. This involves scraping the uterine wall to gather more cells from the lining of the uterus.
If advanced cancer is suspected, other tests may be done, such as the following: