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DES Exposure in Utero

Symptoms & Signs

What are the signs and symptoms of the condition?

A woman who was exposed to DES in uteruo may have symptoms, including:

vaginal spotting

abnormal vaginal bleeding

bleeding or spotting after intercourse

abnormal PAP smear results

abnormal vaginal discharge

painful intercourse

unsuccessful penile penetration during the first sexual encounter

abnormalities in the structure of the uterus, vagina, and cervix. Incompetent cervix, for example, may cause miscarriages and/or premature labor and delivery.

A man who was exposed to DES in utero may have:

underdeveloped or undescended testicles

hypospadias, a condition in which the opening to the urethra is located on the underside of the penis

varicocele, a condition in which the veins of the testicles are enlarged

a small penis

meatal stenosis, which is narrowing of the opening of the urethra on the end of the penis

epididymal cysts, which are noncancerous tumors on the back of the testicles

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