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Ferritin


Overview & Description

Ferritin is a protein found in the blood that stores iron. This test measures the amount of ferritin in the blood serum. Iron is a key factor in red blood cell production.

Who is a candidate for the test?

The ferritin test is done to find how much iron is stored in a person's body. The test is ordered if the doctor suspects that the person has either too much or too little iron in the body.

How is the test performed?

To measure the amount of ferritin in the serum, a blood sample is taken from a vein on the forearm or hand. First, the skin over the vein is cleaned with an antiseptic. Next, a strong rubber tube called a tourniquet is wrapped around the upper arm. This restricts the blood flow through the veins in the lower arm causing them to enlarge. A small needle is inserted into a vein. The tourniquet is removed. Blood flows from the vein through the needle into a syringe or vial. The sample is sent to the lab for testing. After the needle is withdrawn, the puncture site is covered for a short time to prevent bleeding.


Preparation & Expectations

What is involved in preparation for the test?

There is no special preparation for this test.


Results and Values

What do the test results mean?

Abnormally high amounts of ferritin may suggest:

  • alcoholic liver disease
  • hemochromatosis, a genetic disease that causes the body to absorb and store too much iron
  • hemosiderosis, a condition in which iron builds up in the lungs and liver
  • hemolytic anemia, which is caused by destruction of red blood cells
  • Hodgkin's lymphoma, a cancer of the blood
  • megaloblastic anemia, in which the bone marrow produces large, abnormal red blood cells
  • inflammatory disease
  • advanced cancer
  • leukemia, cancer of the blood
  • cirrhosis, which is destruction of the normal liver tissue
  • chronic hepatitis, an inflammation of the liver that lasts at least 6 months
  • Abnormally low amounts of ferritin may be caused by:

  • chronic gastrointestinal bleeding
  • heavy menstrual bleeding
  • iron deficiency anemia, which is a low red blood cell count caused by a deficiency of iron in the diet

  • Attribution

    Author:David T. Moran, MD
    Date Written:
    Editor:Crist, Gayle P., MS, BA
    Edit Date:09/10/02
    Reviewer:Kathleen A. MacNaughton, RN, BSN
    Date Reviewed:09/07/02

    Sources

    Mosby's Diagnostic and Laboratory Test Reference: 4th edition, 1999