Gamma-glutamyltransferase, also known as GGT, is an enzyme that is found mainly in the liver. But it may also be found in the:
GGT levels are measured when a doctor suspects there is damage or disease in the liver or the biliary system.
In order to measure the amount of GGT in the blood, a blood sample is taken from a vein on the forearm or hand. First, the skin over the vein is cleaned with an antiseptic. Next, a rubber tube called a tourniquet is tied around the upper arm. This enlarges the veins in the lower arm by restricting blood flow through them. A fine needle is gently inserted into a vein, and the tourniquet is removed. Blood flows from the vein through the needle and is collected in a syringe or vial for testing in the laboratory. After the needle is withdrawn, the puncture site is covered for a short time to prevent bleeding.
Generally, no preparation is required for this test.
For men, the healthy values for GGT are 2 to 30 U/L.
For women, the healthy range is 1 to 24 U/L.
Abnormal levels of GGT can be found in the following conditions:
In addition, certain medicines that are used to prevent seizures such as tegretol, phenobarbital, and dilantin may be related to abnormal levels of GGT.
Author:Melinda Ratini, DO, MS
Date Written:
Editor:Crist, Gayle P., MS, BA
Edit Date:06/18/02
Reviewer:Kathleen A. MacNaughton, RN, BSN
Date Reviewed:06/13/02