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General Paresis


Treatment & Monitoring

What are the treatments for the disease?

General paresis is treated with high doses of penicillin for two or more weeks. Treatment early in the course of general paresis improves the mental and physical symptoms in about 40% of people.

What are the side effects of the treatments?

Penicillin may cause allergic reactions, rash, or stomach upset.

What happens after treatment for the disease?

Treatment halts the progression of the disease 40% to 50% of the time. Neurological problems improve in 30% to 40% of cases. The cerebrospinal fluid has to be rechecked to be sure that the Treponema organism is completely eliminated. Sometimes, the penicillin treatment has to be repeated. Any new or worsening symptoms should be reported to the healthcare provider.


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