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Malignant Mesothelioma


Symptoms & Signs

What are the signs and symptoms of the disease?

Mesothelioma that affects the pleura can cause these signs and symptoms:

  • chest wall pain
  • pleural effusion, or fluid surrounding the lung
  • shortness of breath
  • wheezing, hoarseness, or cough
  • In severe cases, the person may have many tumor masses. The individual may develop a pneumothorax, or collapse of the lung. The disease may metastasize, or spread, to other parts of the body.

    Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:

  • abdominal pain
  • ascites, or an abnormal buildup of fluid in the abdomen
  • a mass in the abdomen
  • problems with bowel function
  • weight loss
  • In severe cases of the disease, the following signs and symptoms may be present:

  • blood clots in the veins, which may cause thrombophlebitis
  • disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
  • jaundice, or yellowing of the eyes and skin
  • low blood sugar level
  • pleural effusion
  • pulmonary emboli, or blood clots in the arteries of the lungs
  • severe ascites
  • A mesothelioma does not usually spread to the bone, brain, or adrenal glands. Pleural tumors are usually found only on one side of the lungs.


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