Most people use the term "leg" to mean the entire area between the top of the thigh and the ankle. Pain can occur in this part of the body for many reasons.
Pain may occur in one or both legs. There are many different causes, ranging from unimportant to life-threatening.
There are many possible causes of leg pain, including:
There are other causes of leg pain. Sometimes, a cause cannot be found.
When a person complains of leg pain, the healthcare provider will ask some questions about the pain. These may include:
Diagnosis of the cause of leg pain begins with a history and physical exam. Blood tests may be helpful in some cases. For example, a blood test called a complete blood count (CBC) may help diagnose an infection. Imaging tests, such as an ultrasound, can help diagnose blood clots and poor blood flow. X-rays can help diagnose a bone fracture, tumor, or infection.
Many cases of leg pain cannot be prevented, but prevention is related to the cause. For example, atherosclerosis can often be avoided by not smoking, eating a good diet, and exercising regularly. Controlling blood sugar levels with diet, exercise, and medications can sometimes prevent diabetic neuropathy.
Long-term effects are related to the cause of the pain. Pain can be severe and make a person unable to perform normal activities. Chronic pain can also cause stress, sleep disorders, and depression.
Infections can often be treated with antibiotics and may have no long-term effects. A deep venous thrombosis in the leg can break off and travel through the bloodstream to the lungs, a condition called pulmonary embolus.
Leg pain is not contagious and poses no risk to others.
Leg pain can be treated in a number of ways. The treatment is partly related to the cause. Most commonly used are nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen. These can help with many types of pain, such as that due to injury or arthritis. Medications such as gabapentin and amitriptyline may help treat pain due to nerve damage. Cancer pain can often be treated with medications like morphine or meperidine.
The underlying cause of the leg pain may need to be treated as well. For example, someone with a broken leg may need a cast or surgery. Someone with deep blood clots may need to be treated with blood thinners like heparin or warfarin. An infection may need treatment with antibiotics. A person with a bone tumor or cancer may need surgery, chemotherapy, or radiation treatment.
Side effects depend on the treatments used. NSAIDs may cause allergic reactions or stomach upset. Blood thinners may cause abnormal bleeding if the blood gets too thin. Surgery poses a risk of bleeding, infection, and allergic reactions to anesthesia.
Arthritis is often a lifelong condition requiring long-term treatment. An infection may be "cured" by treatment and the person may be able to return to normal activities right away. Cancer may result in death if treatment is not successful.
Monitoring is related to the cause of the pain. For example, those with nerve damage from diabetes need to check their blood sugar levels often. Any new or worsening symptoms should be reported to the healthcare provider.
Author:Adam Brochert, MD
Date Written:
Editor:Duff, Ellen, BA
Edit Date:09/28/00
Reviewer:Eileen McLaughlin, RN, BSN
Date Reviewed:08/09/01
Harrison's Principles of Internal Medicine, Fauci et al., 1998