Stroke Following Carotid Dissection - Stroke from Carotid Dissection
Overview, Causes, & Risk Factors
A stroke is the death of brain tissue that occurs when the brain does not get
enough blood and oxygen. A stroke from carotid dissection occurs when one of
the carotid arteries in the neck is torn, or dissected.
What is going on in the body?
A carotid dissection occurs when the layers of the wall of the carotid artery
break down. Carotid dissection is sometimes caused by an injury to the head or
neck.
The carotid dissection causes a blockage of the artery and impairs blood flow
to the brain. The brain cells then die from lack of oxygen. In turn, the blood also
damages the brain cells. The products released when cells die cause swelling in
the brain. Since the skull doesn't allow much room for expansion, this swelling
can damage the brain tissue even further.
What are the causes and risks of the condition?
Carotid dissection can be brought on by:
head injury
neck injury
severe whiplash injury, which
occurs when the neck is suddenly and forcibly bent backwards and forwards
bouts of violent coughing
surgical procedures involving the neck
The person's risk of stroke from carotid dissection is increased if other
risk factors for stroke are also present.
The American Heart Association has recently issued guidelines for stroke
prevention. The guidelines discuss risk factors for stroke in 3 categories:
nonmodifiable, well-documented modifiable, and less well-documented or
potentially modifiable.
The nonmodifiable factors are ones that cannot be changed by the individual
and include:
increasing age. A person's risk of stroke doubles each year after age
55.
race. Strokes occur approximately twice as often in blacks and Hispanics as
they do in whites.
gender. Men have a 50% higher chance of stroke than women do.
family history of stroke or
transient
ischemic attack (TIA). A TIA is a short, reversible form of stroke
that
may serve as an early warning sign of stroke.
Well-documented modifiable risk factors are those that can be changed by the
individual in conjunction with his or her healthcare provider. These factors
are linked to stroke by strong research findings, and there is documented proof
that changing the risk factor lowers a person's risk of stroke. These factors
include:
high blood pressure
smoking
diabetes
asymptomatic carotid stenosis, or
narrowing of one of the arteries in the neck
sickle cell anemia,
a blood
disorder that forms abnormal red blood cells
high cholesterol
levels in the
blood, including total
cholesterol and
LDL or "bad
cholesterol." Low levels
of HDL or "good
cholesterol" are also
cause for concern.
atrial fibrillation,
an abnormal
heart rhythm
Less well-documented or potentially modifiable risk factors for stroke are
those that have less proof of either a link to stroke or the impact of
modifying the risk factor. These factors include:
obesity
sedentary lifestyle
alcohol abuse
high blood levels of homocysteine, a blood component sometimes associated
with a higher risk of stroke
drug abuse
blood disorders, such as blood that clots easily or deficiencies of various
blood components
hormone replacement
therapy (HRT).
The AHA currently states that the risk of stroke associated with HRT appears
low but needs further study.
use of birth control pills, or oral
contraceptives
inflammatory processes, such as a chronic infection with chlamydia
Several recent studies have identified factors that seem to increase or
decrease the risk of stroke in particular groups of people. These studies,
which warrant further investigation, include these findings:
People who were treated for high
blood
pressure with thiazide diuretics, such as hydrochlorothiazide, had
a
significantly lower stroke risk than people on ACE inhibitors or calcium
channel blockers.
Women ages 39 to 50 who ate more fish and omega-3 polyunsaturated fatty acids had a reduced risk of stroke. This was particularly true in women who did not take aspirin regularly.
Women ages 15 to 44 who had 2 drinks of wine a day had a 40% to 60% lower
risk of stroke than women who did not drink
alcohol.
Phenylpropanolamine, a compound contained in appetite suppressants and cold
remedies, significantly increased the risk of hemorrhagic stroke in women 18 to 49
years of age. The Food and Drug Administration (FDA) has since asked
manufacturers to remove phenylpropanolamine from their products.
In one study, people who were treated in emergency departments for
transient ischemic attacks (TIA) had a 25% chance of having a stroke or other
serious health event within the next 90 days.
Symptoms & Signs
What are the signs and symptoms of the condition?
Stroke from carotid dissection can cause different signs and symptoms,
depending on the area of the brain that is damaged. Signs or symptoms may
include:
problems with movement, such as weakness, clumsiness, or paralysis on
one side of the body
headache
numbness or a lack of feeling on one side of the body
speech impairments, including
slurred speech or difficulty finding the correct word
difficulty doing math or writing
difficulty understanding speech or writing
inability to recognize family members or common objects
dementia, a condition that affects memory, understanding, and the
ability to carry out the normal activities of daily life
facial pain on one side
visual impairments, often described as having a shade pulled over an
eye
personality changes
difficulty swallowing
balance problems, known as ataxia
coma
the inability to breathe on one's own. This may require a person to be put
on an artificial breathing machine, or
ventilator.
Diagnosis & Tests
How is the condition diagnosed?
A magnetic resonance angiogram, which involves injecting a dye into an artery
or blood vessel for better viewing, may be ordered to detect carotid
dissection. In this test, the carotid artery of a person with carotid
dissection will show what is called a string sign. This is described as an
elongated, irregular, narrow column of dye in the artery.
Cranial MRIs and cranial CT
scans may be ordered to show the type, size, and location of the
stroke.
Prevention & Expectations
What can be done to prevent the condition?
Carotid dissection can be prevented by avoiding any trauma to the head or neck.
It's important to use seat belts while driving. Head injuries and neck
injuries can be minimized by following sports safety guidelines for
children, adolescents, and adults.
People can also lower their risk of stroke from carotid dissection by
addressing other risk factors for stroke. The American Heart Association
guidelines for stroke prevention address both modifiable and less
well-documented or potentially modifiable risk factors.
Measures to reduce the modifiable risk of
high blood pressure include:
measurement of blood
pressure in
adults at least every 2 years to screen for
high blood pressure
weight control
physical activity
moderation in alcohol
intake
moderate sodium intake
for those who smoke, quitting
smoking
medications to treat high blood pressure if the person's blood pressure is
over 140/90 after 3 months of these lifestyle modifications, or if the initial
blood pressure is over 180/100
Other measures to reduce an individual's modifiable risk factors for stroke may
include:
smoking cessation
using nicotine
patches, counseling, and formal smoking programs
control of blood sugar levels in a person with diabetes through medication, diet, and exercise
the use of ramipril in people with diabetes. A recent study showed that people with diabetes have a 33% lower risk of ischemic stroke if they take ramipril.
careful evaluation of asymptomatic carotid stenosis to determine the need for surgery. Coronary artery surgery, such as an endarterectomy,
may be
indicated. An endarterectomy opens the narrow portion of the artery and
increases the blood flow to the brain. People with carotid stenosis should
also work closely with their healthcare providers to control other risk factors
for stroke.
semiannual screening of children with
sickle cell anemia, using ultrasound to determine the child's risk
of
stroke
treatment of atrial
fibrillation
with blood thinners such as aspirin or warfarin, depending on the person's age
and other risk factors
monitoring of high levels of total cholesterol or LDL, as well as low
levels of HDL. Depending on the blood levels and the person's other risk
factors, medications to lower cholesterol may be given.
Measures to reduce less well-documented or potentially modifiable risks for
stroke may include:
weight reduction in overweight persons
30 or more minutes of moderate exercise a day for most individuals.
People with heart disease
or
disabilities should be in a medically supervised exercise program.
a healthy diet for preventing heart
disease,
containing at least 5 fruits and vegetables a day
for those who drink
alcohol,
drinking in moderation. The AHA defines moderate drinking as no more than 2
drinks a day for men and 1 drink a day for women.
seeking treatment for drug
abuse
monitoring of blood levels of homocysteine. For most individuals, a
well-balanced diet following the food guide pyramid will provide enough folic
acid and B vitamins to maintain a healthy homocysteine level. For people with
elevated homocysteine levels, supplements containing folic acid and B vitamins
may be recommended.
avoiding the use of oral contraceptives in women with other stroke risk
factors
Some people have early warning signs that they are at risk for strokes. The
most common warning sign is what is known as a transient ischemic
attack, or TIA. This is a type of reversible stroke that often goes
away after a few minutes. These people can often get treatment that will
prevent a stroke in the future. For instance, people may be advised to take
aspirin or have carotid artery surgery to correct a blockage in a
neck artery.
What are the long-term effects of the condition?
Strokes can cause death or permanent disability. Though many people recover
some function in the first several months after a stroke, others show no
improvement. Some people have several small strokes over time and slowly get
worse with each one.
What are the risks to others?
Strokes are not contagious and pose no risk to others.
Treatment & Monitoring
What are the treatments for the condition?
A person with a stroke from carotid dissection is usually treated immediately
with the blood thinner heparin administered through the vein. After heparin,
another blood-thinning medication, warfarin, is taken orally.
If someone has the early warning signs of stroke, the emergency medical system should be contacted immediately.
These signs include a sudden onset of:
severe headache
weakness or numbness of the face,
arm, or leg, especially on one side of the body
dizziness
trouble walking or loss of balance, known as ataxia
confusion
speech impairments, including
trouble speaking or understanding speech
visual impairments
Supportive therapy may also be needed with some strokes. This may include an artificial breathing machine, or
ventilator, and an artificial
feeding tube if the person cannot swallow.
Rehabilitation services can help to improve a person's function after a stroke.
Physical therapy and other therapy, such as speech
therapy or occupational therapy, may be used to maximize
recovery.
What are the side effects of the treatments?
Excessive bleeding from the blood-thinning medications, or anticoagulants, is
possible. People need to avoid activity that may cause bruises or cuts, such as
rough sports or working with sharp tools.
What happens after treatment for the condition?
After the person is stable, treatment of the risk factors for stroke, as well
as the cause of the stroke, is important to prevent further strokes. For
instance, stopping smoking and controlling high blood pressure,
diabetes, and high cholesterol
are advised for most people.
Blood thinners such as warfarin may be discontinued in several months or a year
depending upon the results of a repeat imaging test. The healthcare provider
may discontinue these medications if the angiogram shows that the opening of
the carotid artery is unblocked so that enough blood can flow through the
artery. This is known as a patent artery and is considered to
be at least 50% of normal diameter with a smooth wall.
Many people need assistance of one form or another after a stroke. This may
range from using a walking cane to needing 24-hour-a-day skilled nursing
care. Ongoing therapy to improve function is usually advised for at least 6
months if the person is able.
How is the condition monitored?
If an individual takes blood thinners, blood tests are normally done to assure
the correct dose. These tests let a healthcare provider know if the person's
blood is too "thin" or too "thick," which may require a dosage adjustment. Any
new or worsening symptoms should be reported to the healthcare provider.
Attribution
Author:Tamara Miller, MD
Date Written:
Editor:Ballenberg, Sally, BS
Edit Date:01/31/01
Reviewer:Eileen McLaughlin, RN, BSN
Date Reviewed:07/15/01